The use of a digital health application with patient-reported outcomes is associated with an increase in disease control rate for adults with rheumatoid arthritis (RA), according to a study published online April 14 in JAMA Network Open.
Chun Li, M.D., from the Peking University People’s Hospital in Beijing, and colleagues assessed whether patient-reported outcomes using digital health applications could result in disease control for patients with RA. The analysis included 2,197 adult patients with RA who were randomly assigned to a smart system of disease management (SSDM) group or a conventional care control group.
The researchers found that at month 6, the rate of patients with a disease activity score in 28 joints using the C-reactive protein (DAS28-CRP) of ≤3.2 was 71.0 percent in the SSDM group versus 64.5 percent in the control group (difference between groups, 6.6 percent; 95 percent confidence interval, 2.7 to 10.4 percent; P = 0.001). The rate of patients with a DAS28-CRP of ≤3.2 at month 12 in the control group increased to a level (77.7 percent) that was similar to that of the SSDM group (78.2 percent; difference between groups, −0.2 percent; 95 percent confidence interval, −3.9 to 3.4 percent; P = 0.90).
“This study provides modest clinical value that application-based patient-reported outcomes and intervention could be an effective way to treat patients with RA and may provide evidence for diseases with complex treatment targets,” the authors write.
Chun Li et al, Management of Rheumatoid Arthritis With a Digital Health Application, JAMA Network Open (2023). DOI: 10.1001/jamanetworkopen.2023.8343
JAMA Network Open
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